/* PeaK viewer palette and type, scoped to this standalone calculator. */
:root { font-family: Inter, ui-sans-serif, system-ui, -apple-system, BlinkMacSystemFont, "Segoe UI", sans-serif; color-scheme: light; }
* { box-sizing: border-box; }
body { --bg: #f8fafc; --fg: #334155; --muted: #64748b; --accent: #0369a1; --gold: #d97706; --border: #cbd5e1; --card: #fff; --input: #fff; --shadow: 0 10px 30px -5px rgba(148,163,184,.3); margin: 0; background: var(--bg); color: var(--fg); line-height: 1.55; }
body.dark { color-scheme: dark; --bg: #020617; --fg: #e5e7eb; --muted: #a7b0c2; --accent: #38bdf8; --gold: #d4af37; --border: #334155; --card: #0f172a; --input: #111827; --shadow: 0 20px 40px rgba(0,0,0,.25); }
[hidden] { display: none !important; }
a { color: var(--accent); }
button, input, select { font: inherit; }
button, input, select { min-width: 0; max-width: 100%; border: 1px solid var(--border); border-radius: 8px; background: var(--input); color: var(--fg); padding: 9px 10px; min-height: 42px; }
button { cursor: pointer; margin: 4px 4px 4px 0; }
button:hover { border-color: var(--accent); }
input, select { width: 100%; }
:focus-visible { outline: 3px solid var(--accent); outline-offset: 3px; }
.toolbar, main, footer { width: min(1320px, calc(100% - 40px)); margin-inline: auto; }
.toolbar { display: flex; justify-content: space-between; align-items: center; gap: 20px; padding: 20px 0; border-bottom: 3px solid var(--gold); }
.brand { display: flex; flex-direction: column; text-decoration: none; color: var(--fg); }
.brand strong { font-size: 30px; line-height: 1.1; font-weight: 600; }
.brand span { font-size: 11px; text-transform: uppercase; letter-spacing: 2px; color: var(--muted); }
.intro { width: min(1120px, 100%); margin-inline: auto; padding: 28px 0 14px; }
h1 { font-size: clamp(1.55rem, 3vw, 2rem); line-height: 1.2; margin: 0 0 14px; }
h2 { font-size: 1.15rem; margin: 0 0 12px; }
h3 { font-size: 1rem; margin: 16px 0 8px; }
h4 { font-size: .92rem; margin: 14px 0 4px; }
p { margin: 0 0 14px; }
.eyebrow { color: var(--accent); font-size: .8rem; letter-spacing: .07em; text-transform: uppercase; }
.muted, .field { font-size: .88rem; }
.muted { color: var(--muted); }
.card { padding: 24px; background: var(--card); border: 1px solid var(--border); border-radius: 18px; box-shadow: var(--shadow); min-width: 0; }
.clinical-workflow { width: min(1120px, 100%); margin-inline: auto; }
.clinical-interpretation { width: min(1120px, 100%); margin: 0 auto 12px; }
.result-panel { border: 1px solid color-mix(in srgb, var(--accent) 52%, var(--border)); border-radius: 14px; background: color-mix(in srgb, var(--accent) 7%, var(--card)); box-shadow: var(--shadow); }
.result-banner { position: sticky; top: 16px; z-index: 10; display: grid; grid-template-columns: minmax(0, 1.05fr) minmax(250px, 1fr) minmax(260px, .9fr); grid-template-areas: "identity range sampling" "note note sampling"; gap: 14px 28px; align-items: center; padding: 18px 22px; }
.result-banner[data-result-state="post-cycle"] { grid-template-columns: minmax(0, 1fr) minmax(320px, .85fr); grid-template-areas: "identity sampling" "note sampling"; }
.result-banner[data-result-state="invalid"], .result-banner[data-result-state="empty"] { grid-template-columns: minmax(0, 1fr) minmax(320px, .85fr); grid-template-areas: "identity sampling"; }
.result-identity { grid-area: identity; min-width: 0; }
.result-panel .eyebrow { margin-bottom: 4px; font-size: .72rem; }
.result-panel h2 { margin-bottom: 8px; }
.source-note { margin: 0 0 10px; padding-left: 10px; border-left: 2px solid var(--gold); }
.field { display: flex; flex-direction: column; gap: 6px; min-width: 0; }
.regimen-builder { margin-top: 18px; }
.regimen-header, .dose-row { display: grid; grid-template-columns: minmax(0, 1.6fr) minmax(110px, .6fr) minmax(135px, .7fr) minmax(110px, auto); gap: 12px; }
.regimen-header { padding: 10px 12px 7px; border-bottom: 1px solid var(--border); color: var(--muted); font-size: .78rem; font-weight: 600; }
.rows { margin: 0 0 12px; }
.dose-row { align-items: end; padding: 10px 12px; border-bottom: 1px solid var(--border); }
.dose-row .field { gap: 0; font-size: 0; }
.dose-row input, .dose-row select { font-size: .9rem; }
.dose-row button { justify-self: stretch; margin: 0; padding: 7px 10px; min-height: 42px; font-size: .8rem; }
.add-dose { margin: 0; padding-inline: 14px; }
.mean.primary-value strong { font-size: 2.5rem; }
.mean.primary-value { margin: 0; }
.result-range { grid-area: range; min-width: 0; text-align: center; }
.drr-range { margin: 6px 0 0; font-size: 1rem; font-variant-numeric: tabular-nums; }
.result-label { margin-bottom: 8px; color: var(--muted); font-size: .88rem; font-weight: 600; }
.drr-bar { width: 100%; padding: 4px 5px 0; }
.drr-track { position: relative; height: 8px; margin-top: 24px; border: 1px solid var(--accent); border-radius: 999px; background: color-mix(in srgb, var(--accent) 18%, var(--card)); }
.drr-marker { position: absolute; top: 50%; width: 3px; height: 20px; border-radius: 2px; background: var(--accent); transform: translate(-50%, -50%); }
.drr-marker-label { position: absolute; bottom: calc(100% + 4px); left: 50%; color: var(--muted); font-size: .72rem; font-weight: 600; line-height: 1; white-space: nowrap; transform: translateX(-50%); }
.drr-marker[data-label-align="start"] .drr-marker-label { left: 0; transform: none; }
.drr-marker[data-label-align="end"] .drr-marker-label { left: 100%; transform: translateX(-100%); }
.drr-axis { display: flex; justify-content: space-between; margin-top: 7px; color: var(--muted); font-size: .72rem; }
.unavailable { margin: 12px 0; color: var(--gold); font-size: 1.3rem; font-weight: 600; }
.inline-error { max-width: 42rem; border-left: 3px solid var(--gold); padding-left: 12px; color: var(--muted); font-size: .88rem; }
.mean strong { font-size: 2.2rem; font-weight: 600; color: var(--accent); font-variant-numeric: tabular-nums; }
.mean span { color: var(--muted); font-size: .9rem; }
.sampling-control { grid-area: sampling; min-width: 0; padding-left: 24px; border-left: 1px solid var(--border); }
.sampling-control p { margin: 8px 0 0; }
.post-cycle-note { grid-area: note; margin: 0; }
.scope-signpost { margin: 18px 0 0; }
summary { cursor: pointer; font-weight: 600; padding: 12px 0; }
.method-disclosure { width: min(1120px, 100%); margin: 22px auto 0; }
.method-disclosure > summary { font-size: 1.08rem; }
.method-disclosure[open] > summary { margin-bottom: 8px; border-bottom: 1px solid var(--border); }
.method-body { padding-top: 8px; }
.table-scroll { overflow-x: auto; }
table { width: 100%; border-collapse: collapse; font-size: .8rem; margin-bottom: 16px; }
th, td { text-align: left; padding: 8px; border-bottom: 1px solid var(--border); vertical-align: top; }
footer { padding: 28px 0; color: var(--muted); font-size: .9rem; }
.footer-inner { width: min(1120px, 100%); margin-inline: auto; }
.skip-link { position: absolute; top: -100px; left: 16px; padding: 10px; background: var(--card); z-index: 1; }
.skip-link:focus { top: 8px; }
@media (max-width: 820px) {
  .result-banner { position: static; grid-template-columns: minmax(0, 1fr); grid-template-areas: "identity" "range" "sampling"; gap: 16px; }
  .result-banner[data-result-state="post-cycle"] { grid-template-columns: minmax(0, 1fr); grid-template-areas: "identity" "sampling" "note"; }
  .result-banner[data-result-state="invalid"], .result-banner[data-result-state="empty"] { grid-template-columns: minmax(0, 1fr); grid-template-areas: "identity" "sampling"; }
  .result-range { text-align: left; }
  .sampling-control { padding: 16px 0 0; border-top: 1px solid var(--border); border-left: 0; }
}
@media (max-height: 700px) and (min-width: 821px) { .result-banner { position: static; } }
@media (max-width: 620px) {
  .toolbar, main, footer { width: calc(100% - 24px); }
  .card, .result-banner { padding: 16px; }
  .regimen-header { display: none; }
  .dose-row { grid-template-columns: minmax(0, 1fr) minmax(0, 1fr); gap: 10px; padding-inline: 0; }
  .dose-row .field { gap: 6px; color: var(--muted); font-size: .88rem; }
  .dose-row > .field:first-child, .dose-row button { grid-column: 1 / -1; }
  .dose-row button { justify-self: start; }
}